Anesthesia: Essays and Researches

REVIEW ARTICLE
Year
: 2021  |  Volume : 15  |  Issue : 1  |  Page : 4--7

Fentanyl-induced respiratory depression: A narrative review on the possible single-nucleotide polymorphism


Prabha Udayakumar1, Srisruthi Udayakumar2 
1 Department of Anesthesiology, Sri Ramakrishna Hospital, Coimbatore, Tamil Nadu, India
2 Department of Biotechnology, PSG College of Technology, Coimbatore, Tamil Nadu, India

Correspondence Address:
Dr. Prabha Udayakumar
Department of Anesthesiology, Sri Ramakrishna Hospital, Coimbatore - 641 044, Tamil Nadu
India

Opioid-related respiratory depression is a serious clinical problem as it can cause multiple deaths and anoxic brain injury. Genetic variations influence the safety and clinical efficacy of fentanyl. Pharmacogenetic studies help in identifying single-nucleotide polymorphisms (SNPs) associated with fentanyl causing respiratory depression and aid clinician in personalized pain medicine. This narrative review gives an insight of the common SNPs associated with fentanyl.


How to cite this article:
Udayakumar P, Udayakumar S. Fentanyl-induced respiratory depression: A narrative review on the possible single-nucleotide polymorphism.Anesth Essays Res 2021;15:4-7


How to cite this URL:
Udayakumar P, Udayakumar S. Fentanyl-induced respiratory depression: A narrative review on the possible single-nucleotide polymorphism. Anesth Essays Res [serial online] 2021 [cited 2021 Dec 3 ];15:4-7
Available from: https://www.aeronline.org/article.asp?issn=0259-1162;year=2021;volume=15;issue=1;spage=4;epage=7;aulast=Udayakumar;type=0