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REVIEW ARTICLE
Year : 2013  |  Volume : 7  |  Issue : 3  |  Page : 302-306

Sugammadex: A revolutionary drug in neuromuscular pharmacology


1 Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry, India
2 Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India

Correspondence Address:
Dewan Roshan Singh
Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry - 607 402
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0259-1162.123211

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Sugammadex (ORG 25969) is a unique neuromuscular reversal drug; a novel cyclodextrin, the first in a new class of selective relaxant binding agents, which reverse neuromuscular blockade (NMB) with the aminosteroid non-depolarizing muscle relaxants rocuronium and vecuronium. Sugammadex can reverse moderate or deep NMB. The clinical use of sugammadex promises to eliminate many of the shortcomings in current anesthetic practice with regard to antagonism of rocuronium and other aminosteroid muscle relaxants.


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