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Year : 2010  |  Volume : 4  |  Issue : 1  |  Page : 15-19

A comparative study of intubating conditions of rocuronium bromide and suxamethonium in adult patients

Department of Anesthesiology, M.P. Shah Medical College, Jamnagar - 361 008, Gujarat, India

Correspondence Address:
Shobhana Gupta
Qt. No. - B/8/A, Shree M.P. Shah Medical College Campus, Jamnagar - 361 008, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0259-1162.69300

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Aim: Intubating conditions after Suxamethonium, a time tested popular short acting depolarizing neuromuscular blocking agent, and Rocuronium, a recently introduced intermediate acting non depolarizing neuromuscular blocking agent, with Thiopentone as the sole induction agent, were compared in this study. Materials and Methods: The patients were divided into two groups, each consisting of 30 patients: group a patient's received Rocuronium bromide, 0.6 mg/kg and group B patients received Suxamethonium chloride 1.5 mg/kg. In both the groups, jaw relaxation and vocal cord relaxation were considered for atraumatic laryngoscopy at 60 seconds or, if needed, at 75 seconds and then at 90 seconds. Results: Intubation conditions were rated as excellent in 90% and good in 10% of the patients who received Rocuronium, and excellent in 100% of the patients who received Suxamethonium. Conclusion: It is concluded from this study that intubation can be performed under good to excellent conditions at 60-90 seconds after a bolus dose of Rocuronium of 0.6 mg/kg. The result of this study indicates that this new nondepolarizing neuromuscular blocking agent may be considered as a valuable alternative to Suxamethonium for rapid tracheal intubation, i.e., within 60 seconds, even after induction with Thiopentone as the sole anesthetic agent.

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